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TOPPIC: Randomised controlled trial of 6-Mercaptopurine (6MP) versus placebo to prevent recurrence of Crohn's disease following surgical resection

Trial Overview

AcronymTOPPIC
NumberISRCTN89489788
Protocol Linkhttp://www.isrctn.com/ISRCTN89489788
Public Trial Registry Linkhttp://www.isrctn.com/ISRCTN89489788
Published Results Linkhttp://thelancet.com/pdfs/journals/langas/PIIS2468-1253(16)30078-4.pdf
StatusPublished
CategoryIBD
Treatment CourseAdjuvant, palliative or post-op

Trial Description

Multi-center double-blind randomised placebo-controlled trial in Crohn's disease. Patients randomised to treatment with 6MP or matching placebo. Primary Outcome measures are post-operative recurrence of Crohn's disease requiring anti-inflammatory rescue therapy and time of recurrence.

Chief Investigator

Jack Satsangi
Professor
Profile Link

Lead Centre

Western General Hospital
Crewe Road South
Edinburgh
EH4 2XU
UK
Website

Additional Information

Full Research Summary
ESCP Affiliates