Eloy Espin-Basany

eloy espin basany Professional titles:
Chief of Colo-rectal Surgery Unit, Hospital Valle de Hebron, Barcelona; Professor of Surgery, Universitat Autonoma de Barcelona

Dates of primary qualification: 1990

Current Institution:
Hospital Valle de Hebron, Universitat Autonoma de Barcelona, Spain

Title of invited presentation:
New techniques for perianal fistula

Learning objectives:
At the conclusion of the presentation, participants should be able to: a) understand the rationale of the new techniques to treat anal fistula; b) know the published data of efficacy of these new techniques; c) comprehend the limitations of the new techniques.

Summary of clinical/research background

Our research is both basic and clinical. In basic research we have two main teams, one working in nanotechnoclogy, cellular quiescence and response to chemotherapy and another one working in IBD basic research.

In clinical research we have our own research in pelvic floor disease, IBD and cancer and collaborations with other research centers to do multicentric trials and research (laparoscopy, cancer, anal fissure, incontinence, rectal prolapse, etc).

Relevant peer reviewed publications within last 5 years

Preoperative chemoradiotherapy wih UFT and leucovorin in patients with advanced rectal cancer: a phase II study.
Radiotherapy and oncology, 2008, Dec; 89 (3): 263-9.
Laparoscopic assisted rectosigmoidectomy with ileal loop interposition. Surgical treatment of Chagasic megacolon. Diseases of the Colon & Rectum; 2008, (51): 1421 (Multimedia article)
Prospective multicentre clinical trial of stapled transanal rectal resection for obstructive defecation syndrome. British Journal of Surgery 2008; 95: 1521-1527
Lactobacillus casei downregulates commensals inflammatory signals in Crohn’s disease. Inflamm Bowel Dis 2009; 15: 275-283
STARR with Contour Transtar: prospective multicentre european study. Colorectal Dis 2009 , 11 (9), 821-827
Prosthetic mesh in parastomal hernia prevention. laparoscopic approach. Dis Colon & Rectum 2009; 52: 1006
Quality of mesorectum after laparoscopic resection for rectal cancer. Results of an audited teaching programme in Spain. Colorectal Dis 2010 , 12 (1),24-32
Aprataxin tumor levels predict response of colorectal cancer patients to irinotecan-based treatment. Clin Cancer Res. 2010 Apr 15;16(8):2375-82. Epub 2010
Anal fistula plug is a valid alternative option for the treatment of complex anal fistula in the long term. Int J Colorectal Dis 2010 (12) 1487-93
Multivisceral resection for colon cancer: analysis of prognostic factors. Dig Surg 2010; 27: 238-245
Surgical site infection in elective operations for colorectal cancer after the application of preventive measures. Arch Surg 2011; 146: 606-612E).
Risk factors for surgical site infection after elective resection for rectal cancer. A multivariate analysis on 2131 patients. Colorectal Dis. 2011 Aug 30. doi: 10.1111/j.1463-1318.2011.02798.x. e95-102
Influence of rescrubbing before laparotomy closure on abdominal wound infection after colorectal surgery. Results of a multicentric randomized clinical trial. Arch Surg 2012; 147 (7): 614-620
Brush border myosin Ia has tumor suppresor activity in the intestine. PNAS 2012; 109 (5): 1530-1535
B-catenin confers resistance to PI3K and AKT inhibitors and subverts FOXO3a to promote metastasis in colon cancer. Nat Med 2012, Mayo 20, doi: 10.1038/nm.2772
Laparoscopic versus open surgery for rectal cancer: results of a prospective multicentre analysis of 4,970 patients. Surg Endosc. 2012 Jun 27. [Epub ahead of print]
hSMC2, a Core Subunit of Human Condensin Complex, is a Novel Transcriptional Target of the Wnt Signaling Pathway and a New Therapeutic Target J Biol Chem 2012; 287: 43472-43481 doi/10.1074/jbc.M112.428466
Use of a prosthetic mesh to prevent parastomal hernia during laparoscopic abdominoperineal resection: a randomized controlled trial. Hernia 2012, Online July, 11, 2012.