Michael J Stamos

Summary of clinical/research background

Dr Michael Stamos has been an active clinician/educator and researcher in the field of colon and rectal surgery for the past two plus decades. He began his career in the city of Los Angeles after completing his training at the Ochsner Clinic in New Orleans under Drs. John Ray, Byron Gathright and Terry Hicks. For a little over 10 years, he worked at the county hospital of UCLA, and cared for many patients with advanced diseases due to limited health care access. It is here that he developed an interest in appendicitis, and helped establish non operative treatment of advanced appendicitis as a viable option. In 2002 he moved to Orange County California to establish the Division of Colon and Rectal Surgery at the University of California, Irvine. He has since risen to the leadership of the department, assuming the position of Chair in 2010. The Colon and Rectal Surgery Division has grown to 4 members and they are known for their expertise in minimally invasive (laparoscopic and robotic) surgery. They also have established themselves as a productive research group, emphasizing clinical trials and outcomes research. Most recently, Dr. Stamos has been successful in establishing and leading a clinical collaborative between all 5 University of California Medical Centers (UC Irvine, UCLA, UC San Francisco, UC San Diego and UC Davis), and they have been awarded a large research grant to support their work.

Current studies:

• The PILLAR II Multicenter Study (Perfusion) Assessment in Laparoscopic Left Anterior Resection (Novadaq) -Overall study PI
• Multicenter, Prospective, Observational Study of GORE® BIO-A® Fistula Plug for Use in Anal Fistula Repair CS157-Overall study PI
• RObotic versus LAparoscopic Resection for Rectal (ROLARR) cancer: An international, multicentre, prospective, randomized, controlled, unblinded, parallel-group trial of robotic-assisted versus laparoscopic surgery for the curative treatment of rectal cancer
• UCI 05-25 Timing of Rectal Cancer Response to Chemoradiation. Multi-Center Study(UCSF/NCI/City of Hope/MSKCC)
• The University of California Irvine Medical Center Inflammatory Bowel Disease Research Registry
• Phase IIa Clinical Biomarker Trial of Aspirin and Arginine Restriction in Colorectal Cancer Patients
• UCI 07-70: A Phase IIA Randomized, Double-Blind Trial of Erlotinib in Inhibiting EGF Receptor Signaling In Aberrant Crypt Foci of the Colon
• A prospective and retrospective database of colorectal surgery patients having procedures and/or operations performed at UCI Medical Center Principal Investigator
• Phase I/II study of Pre-Operative Neoadjuvant Photodynamic Therapy in Treating Colon Cancer
• Randomized clinical trial comparing the use of perioperative epidural analgesia to conventional intravenous narcotics and NSAIDS for patients undergoing laparoscopic colorectal resection
• SWOG S0820: A Double Blind Placebo-Controlled Trial of Eflornithine and Sulindac to Prevent Recurrence of High Risk Adenomas and Second Primary Colorectal Cancers in Patients with Stage 0-III Colon Cancer, Phase III (MP Version 3/31/2011)
• A Single Blind, Randomized, Controlled Study to Evaluate the Safety and Effectiveness of EVICEL® as an Adjunct to Gastrointestinal Anastomosis Techniques (Ethicon Biosurgery)
• Randomized Control Trial of the Use and Effect of Colonoscopy Simulator for Training
• Multi-Center, Single Blinded, Randomized Controlled Trial of Formal Instructional Video vs. Standard Preparation Prior to Laparoscopic Right Colectomy for General Surgery Residents

Relevant peer reviewed publications within last 5 years

Manuscripts:

• Stamos MJ, Russell WA: (Discussion) Use and Outcomes of Laparoscopic-Assisted Colectomy for Cancer in the United States. Arch Surg 2008; 143(9) 839-40
• Emil S, Huerta S, Stamos MJ: Functional Jejunal Obstruction Following Jejunal Atresia Repair: Presentation in Adulthood. Am Surg 2008; 74(11):1121-3
• Nguyen NT, Reavis KM, Hinojosa MW, Smith BR, Stamos MJ: A Single-Port Technique for Laparoscopic Extended Stapled Appendectomy. Surg Innovation 2009; 16(1):78-81
• Nguyen AV, Martinez M, Stamos MJ, Moyer MP, Planutis K, Hope C, Holcombe RF: Results of a phase I pilot clinical trial examining the effect of resveratrol and grape powder on Wnt pathway target gene expression in colonic mucosa and colon cancer. Cancer Manag Res 2009; 1: 25–37
• Wray C, Hinojosa MW, Ziogas A, Le H, Stamos MJ, Zell JA: Tumor subsite location within the colon is prognostic for survival after colon cancer diagnosis. Dis Colon Rectum 2009; 52(8):1359-66
• Hinojosa MW, Parikh DA, Menon R, Wirth GA, Stamos MJ, Mills S: Recent Experience with Abdominal Perineal Resection with Vertical Rectus Abdominis Myocutaneous Flap Reconstruction Following Preoperative Pelvic Radiation. Am Surg 2009; 75(10): 995-99
• Barleben A, Gandhi D, Nguyen XM, Chen F, Mills S, Stamos MJ: Is Laparoscopic Surgery Appropriate in Patients Who Have Had Previous Abdominal Surgery? Am Surg 2009; 75(10): 1015-1019, PMID:19886156
• Khanifar E, Stamos MJ, Billings TL, Wu M: Contemporary evaluation of colorectal carcinoma in specimens from endoscopic biopsies. LabMedicine 2009; 40(10), 617-24
• Nguyen B, Barleben A, Buchberg B, Stamos MJ, Mills S: Removal of Phytobezoar Through Exploratory Laparoscopy: A Case of Small Bowel Obstruction. Open Access Surg 2010; (3): 59 – 61
• Buchberg B, Masoomi H, Choi H, Bergman H, Mills S, Stamos MJ: A Tale of Two (Anal Fistula) Plugs: Is There a Difference in Short Term Outcomes? Am Surgeon 2010; 76 (10), 1150-1153 PMID:21105632.
• Baxter NN, MacLean AR, Stamos MJ, McLeod RS, Canadian Association of General Surgeons, the American College of Surgeons, the Canadian Society of Colorectal Surgeons, and the American Society of Colorectal Surgeons: Evidence Based Reviews in Surgery-Colorectal Surgery. Dis Colon Rectum 2010; 53 (10): 1708-1711
• Tung VS, Buchberg B, Masoomi H, Reavis K, Nguyen N, Mills S, Stamos MJ: No Visible Scar (NVIS) Colectomy: A New Approach to Minimal Access Surgery to the Colon. Surg Innov 2010 Dec ; 18:79-85, 2011 PMID: 21189268
• Masoomi H, Buchberg B, Magno C, Mills S, Stamos MJ: Trends in Diverticulitis Management in the United States from 2002 to 2007. Arch Surg. 2011 Apr; 146 (4): 400-6 PMID: 21173283
• Nguyen NT, Masoomi H, Laugenour K, Sanaiha Y, Reavis K, Mills S, Stamos MJ: Predictive Factors of Mortality in Bariatric Surgery: Data from the Nationwide Inpatient Sample. Surg Aug 2011;150 (2):347-51
• Masoomi H, Buchberg B, Tung VS, Magno C, Stamos MJ, Mills S: Outcomes of Laparoscopic Versus Open Colectomy in Elective Surgery for Diverticulitis.
  World J Surg 2011 Sep; 35(9):2143-8
• Pan C, Zioga A, Buchberg B, Raj K, Mills SD, Stamos MJ, Zell JA: Timing of Radiation Therapy, Perioperative Lymph Node Retrieval, and Survival in Rectal Cancer. Dis Colon Rectum 2011; 54 (5): 526–534 PMID: 21471752
• Buchberg B, Masoomi H, Lusby K, Choi J, Barleben A, Magno C, Lane J, Nguyen N, Mills S, Stamos MJ: Incidence and Risk Factors of Venous Thromboembolism in Colorectal Surgery: Does Laparoscopy Impart an Advantage? Arch Surg 2011; 146 (6): 739-43 PMID:21690452
• Raj KP, Taylor TH, Wray C, Stamos MJ, Zell JA: Risk of Second Primary Colorectal Cancer among Colorectal Cancer Cases: A Population-Based Analysis. J Carcinog 2011; 10:1-10 PMID: 2148365
• Carmichael J, Masoomi H, Mills S, Stamos MJ, Nguyen NT: Utilization of Laparoscopy in Colorectal Surgery for Cancer at Academic Medical Centers: Does Site of Surgery Affect Rate of Laparoscopy? Am Surg Oct 2011; 77(10):1300-4
• Masoomi H, Buchberg B, Reavis KM, Mills SD, Stamos MJ, Nguyen NT: Outcomes of Laparoscopic and Open Appendectomy for Acute Appendicitis in Patients with Acquired Immunodeficiency Syndrome Am Surg Oct 2011;77(10):1372-6. PMID: 22127092
• Masoomi H, Mills SD, Dolich MO, Dang P, Carmichael JC, Nguyen NT, Stamos MJ: Factors Predictive of Venous Thromboembolism in Bariatric Surgery. Am Surg Oct 2011; 77(10):1403-6. PMID: 22127099.
• Nguyen NT, Shapiro C, Masoomi H, Laugenour K, Elliott C, Reavis K, Stamos MJ: Laparoscopic Enucleation or Wedge Resection of Benign Esophagogastric Pathology: Analysis of 44 Consectutive Cases. Am Surg Oct 2011;77(10):1390-4
• Buchberg B, Mills S, Stamos, MJ: The Use of a Compression Device as an Alternative to Hand Sewn and Stapled Colorectal Anastomoses: Is Three a Crowd? J Gastrointest Surg. 2011 Nov; 15 (2):304-10, PMID: 21063913.
• Nguyen NT, Rudersdorf PD, Smith BR, Reavis K, Nguyen XM, Stamos MJ: Management of Gastrointestinal Leaks After Risk Facophagectomy: Conventional Treatments vs. Endoscopic Stenting. J Gastrointest Surg. Nov 2011; 15(11):1952-60
• Masoomi H, Kim H, Reavis K, Mills S, Stamos MJ, Nguyen NT: Analysis of Factors Predictive of Gastrointestinal Leak in Laparoscopic and Open Gastric Bypass. Arch Surg 2011; 146 (9):1048-1051
• Masoomi H, Mills SD, Dolich MO, Ketana N, Carmichael JC, Nguyen NT, Stamos MJ: Comparison of Outcomes of Laparoscopic Versus Open Appendectomy in Adults: Data from the Nationwide Inpatient Sample (NIS), 2006-2008. J Gastrointest Surg Dec 2011; 1 (12):2226-31.
• Smith BR, Diniz S, Stamos MJ, Nguyen N: Deep Venous Thrombosis After General Surgical Operations at a University Hospital: Two-Year Data From the ACS NSQIP.Arch Surg. Dec 2011;146 (12):1424-1427. PMID:22288087
• Nguyen NT, Nguyen XT, Reavis KM, Elliott C, Masoomi H, Stamos MJ: Minimally Invasive Esophagectomy with and without Gastric Ischemic Conditioning. Surg Endosc 2011 Dec 17; doi: 10.1007/s00464-011-2083-5 [Epub ahead of print] Jun 2012; 203 (6): 1637-1641
• Masoomi H, Nguyen NT, Dolich MO, Wikholm L, Naderi N, Mills S, Stamos MJ: Comparison of Laparoscopic versus Open Appendectomy for Acute Nonperforated and Perforated Appendicitis in the Obese Population. Am J Surg. Dec 2011; 202 (6):733-8 PMID:21992808
• Carmichael JC, Stamos MJ: Transanal Excision of Rectal Cancer: a work in progress.Oncology (Williston Park). Dec 2011; 25 (14):1329-30. PMID: 22329183
• Masoomi H, Nguyen NT, Dolich MO, Mills SD, Carmichael JC, Stamos MJ: Comparisons of Laparoscopic Versus Open for Acute Non-perforated and Perforated Appendicitis in Obese Population. Dec 2011: 202 (6): 733–739.
• Masoomi H, Carmichael JC, Mills SD, Noor K, Dolich MO, Stamos MJ: Predictive Factors of Splenic Injury in Colorectal Surgery: Data from the Nationwide Inpatient Sample, 2006-2008. Arch Surg. 2012; 147(4):324-329. PMID: 22184130
• Masoomi H, Mills S, Dolich MO, Ketana N, Carmichael JC, Nguyen NT, Stamos MJ: Does Laparoscopic Appendectomy Impart an Advantage over Open Appendectomy in Elderly Patients? World J Surg. Mar 2012. [Epub ahead of print] PMID: 22407087 Jul 2012; 36 (7): 1534-1439
• Masoomi H, Reavis K, Smith BR, Kim H, Stamos MJ, Nguyen NT: Risk Factors for Acute Respiratory Failure in Bariatric Surgery: Data from the Nationwide Inpatient Sample (NIS), 2006-2008. SOARD Uncorrected Proof avail online Mar 2012 http://dx.doi.org/10.1016/j.soard. 2012.01.025
• Amini N, Haydel D, Reisian N, Sempa G, Chu JL, Wang Q, Zhao GH, Stamos MJ, Wu MLC: Colorectal Stents Orient Specimens and Induce Artifacts That Mimic Crohn Disease. Int’l J of Path Apr 2012; 20 (2): 161-168
• Smith BR, Reavis K, Nguyen NT, Nguyen XT, Masoomi H, Stamos MJ: Strategic Laparoscopic Surgery for Improved Cosmesis in General and Bariatric Surgery: Analysis of Initial 127 Cases. J Laparoendosc Adv Surg Tech A. [Epub ahead of print] PMID: 22393928 May 2012; (22) 4: 355-361
• Masoomi H, Kang CY, Chaudhry O, Pigazzi A, Mills S, Carmichael JC, Stamos MJ: Predictive Factors of Early Bowel Obstruction in Colon and Rectal Surgery: Data from the Nationwide Inpatient Sample, 2006-2008. JACS [Epub ahead of print] PMID: 22464661 May 2012; 215 (5): 831-837
• Masoomi H, Mills S, Dolich MO, Ketana N, Carmichael JC, Nguyen NT, Stamos MJ: Comparison of Outcomes of Laparoscopic Versus Open Appendectomy in Children: Data from the Nationwide Inpatient Sample (NIS), 2006-2008. World J Surg 2012; 36 (3):573-8
• Kang CY, Halabi WJ, Luo R, Pigazzi A, Nguyen NT, Stamos, MJ: Laparoscopic Colorectal Surgery: A Better Look Into the Latest Trends. Arch Surg Aug 2012; 147 (8):724-31. Epub April 2012 PMID: 22508667
• Masoomi H, Ziogas A, Lin, BS, Barleben A, Mills S, Stamos MJ, Zell, JA: Population-Based Evaluation of Adenosquamous Carcinoma of the Colon and Rectum. Dis Colon Rectum May 2012; 55 (5): 509-514
• Kong AP, Stamos MJ: Anorectal Complaints: Office Diagnosis and Treatment (Part 1). Consultant, Aug, 2012 52:8; 567-570
• Masoomi H, Kang C, Chen A, Mills SD, Dolich MO, Carmichael JC, Stamos MJ: Predictive Factors of In-Hospital Mortality in Colon and Rectal Surgery. JACS 2012 Aug; 215 (2):255-61. Epub May 2012
• Kang CY, Halabi WJ, Chaudhry OO, Nguyen V, Pigazzi A, Carmichael JC, Mills S, Stamos MJ: Risk Factors for Anastomotic Leakage After Anterior Resection for Rectal Cancer. JAMA Surg, Jan 2013;148 (1): 65-71. Epub Arch Surg Sept. 2012
• Kong AP, Stamos MJ: Anorectal Complaints: Office Diagnosis and Treatment (Part 2). Consultant, 2012 Sept 52 (9) 633-636
• Masoomi H, Nguyen NT, Stamos MJ, Smith BR: Overview of Outcomes of Laparoscopic and Open Roux-en-Y Gastric Bypass in the United States. Surg Technol Int. 2012 Sep 30;XXII. pii: sti22/15. [Epub ahead of print]
• Masoomi H, Mills S, Dolich MO, Ketana N, Carmichael JC, Nguyen NT, Stamos MJ: Does Primary Anastomosis Have Any Advantages over Hartmann’s Procedure in Acute Diverticulitis? Dig Surg 2012; 29: 315-320 DOI:10:1159/000342549 published online October 15, 2012
• Masoomi H, Nguyen B, Smith BR, Stamos MJ, Nguyen NT: Predictive factors of acute respiratory failure in esophagectomy for esophageal malignancy. Am Surg. 2012 Oct; 78 (10):1024-8
• Nguyen NT, Nguyen B, Nguyen VQ, Ziogas A, Hohmann S, Stamos MJ: Outcomes of Bariatric Surgery Performed at Accredited vs Nonaccredited Centers. JACS 2012 Oct; 215 (4):467-74
• Kang CY, Carmichael JC, Friesen J, Stamos MJ, Mills S, Pigazzi A: Robotic-assisted extralevator abdominoperineal resection in the lithotomy position: technique and early outcomes. Am Surg. 2012 Oct; 78(10):1033-7. PMID: 23025934
• Kang CY, Chaudhry OO, Halabi WJ, Nguyen V, Carmichael JC, Mills S, Stamos MJ: Risk factors for postoperative urinary tract infection and urinary retention in patients undergoing surgery for colorectal cancer. Am Surg. 2012 Oct; 78 (10):1100-4. PMID: 23025950
• Kang CY, Chaudhry OO, Halabi WJ, Nguyen V, Carmichael JC, Stamos MJ, Mills S: Outcomes of laparoscopic colorectal surgery: data from the Nationwide Inpatient Sample 2009.Am J Surg. 2012 Oct 31
• Kang C, Mills SD, Pigazzi A, Carichael JC, Halabi W, Nguyen N, Stamos MJ: A Nationwide Analysis of Laparoscopy in High-Risk Colorectal Surgery Patients. J Gastrointest Surg. 2012 Dec 1 PubMed 23212528.
• Seery TE, Ziogas A, Lin BS, Pan CG, Stamos MJ, Zell JA: Mortality Risk After Preoperative Versus Postoperative Chemotherapy and Radiotherapy in Lymph Node- Positive Rectal Cancer. J Gastrointest Surg. 2012 Dec 14
• Al-Rubaie A, Stamos MJ, Pigazzi A, Mills SD, Carmichael JC: The Association of Hospital Volume with Rectal Cancer Surgery Outcomes. Int’l J of Colorectal Dis 2013 Feb; 28 (2): 191-6 PMID: 22842664
• Lin AY, Carmichael JC, Finlayson E, Gibbons MM, Ko CY, McLemore EC, Mills SD, Pigazzi A, Ramamoorthy SL, Troppmann KM, Varma MG, Stamos MJ: Universities of California Colorectal Surgery Collaborative Mission Statement. Seminars in Colon and Rectal Surgery Dec 2012; 23 (4): 192-94
• Masoomi H, Luo R, Mills S, Carmichael J, Senagore A, Stamos MJ: Compression Anastomosis Ring Device in Colorectal Anastomosis: A Review of 1,180 Patients. Am J Surg. January 2013; 205(4):447-51
• Halabi WJ, Kang CY, Ketana N, Lafaro KJ, Nguyen VQ, Stamos MJ, Imagawa DK, Demirjian AN: Surgery for Gallstone Ileus: A Nationwide Comparison of Trends and Outcomes. Ann Surg. 2013 Jan 4. [Epub ahead of print] PMID: 23295322
• Patel MS, Mowlds DS, Bhavraj K, Foe-Parker JE, Rama A, Jafari F, Whealon MD, Salibian A, Hoyt DB, Stamos MJ, Endres JE, Smith BR: Early Intervention to Promote Medical Student Interest in Surgery and the Surgical Subspecialties. J Surg Educ. 2013 Jan; 70(1):81-6 PMID: 23337675
• Jafari MD, Lee K, Halabi W, Mills SD, Carmichael JC, Stamos MJ, Pigazzi A: The Use of Indocyanine Green Fluorescence Dye to Assess Anastomotic Tissue Perfusion during Robotic-Assisted Laparoscopic Low Anterior Resection. Surg Endosc 2013 Feb 13 [Epub ahead of print] PMID: 23404152
• Halabi W, Kang CY, Jafari MD, Nguyen VQ, Carmichael JC, Mills SD, Pigazzi A, Stamos MJ: Colonic Volvulus in the United States. Trends, Outcomes, and Predictors of Mortality. Ann Surg 2013 Mar 18 [Epub ahead of print] PMID: 23511842
• Halabi W, Jafari MD, Nguyen VQ, Carmichael JC, Mills SD, Stamos MJ, Pigazzi A: A Nationwide Analysis of the Use and Outcomes of Epidural Analgesia in Open Colorectal Surgery. J Gastro Surg 2013 Jun; 17(6):1130-7. PubMed PMID: 23595885

Books edited:

• Beck DE, Roberts PL, Rombeau JL, Stamos MJ, Wexner SD (Eds): The ASCRS Manual of Colon and Rectal Surgery. Springer 2009
• Lange V: Be A Survivor. Colorectal Cancer Treatment Guide, Second Edition. Stamos MJ, Carmichael JC, Mills SD, Pigazzi A, Wenzel L, Zell JA (Consultants), Lange V (Ed), Lange Productions 2011
• Beck DE, Roberts PL, Saclarides TJ, Senagore AJ, Stamos MJ, Wexner SD (Eds): Colon and Rectal Surgery: ASCRS Textbook. Springer Second Edition , 2011
• Bailey HR, Billingham R, Snyder M, Stamos MJ (Eds) Colon and Rectal Surgery, an Illustrated Manual. Elsevier 2012

Book chapters:

• Kong AP, Stamos MJ: Acute Abdomen in Bongard FS, Sue DY, Vintch JRE (eds): Current Diagnosis & Treatment: Critical Care, Ch 32 pp 696-702. Third Edition. McGraw Hill Medical 2008
• Stamos MJ: Appendicitis In: General Surgery: Principles and International Practice 2nd Edition. Bland KI, Buchler MW, Csendes A, Garden OJ, Sarr MG, Wong J. Springer Verlag London Ltd 2009
• Stamos MJ, Murrell Z: Reoperation for Diverticular Disease In: Reoperative Pelvic Surgery. Billingham RP, Kobayashi K, Peters W (Eds.) Springer 2009; 285-288
• Arnell T, Stamos MJ: Anorectal Disorders In: Educational Review Manual in General Surgery, 8th Edition, Wilson SE (Ed.) Castle Connolly Graduate Medical Publishing LLC 2009; Ch 13, 383-422
• Mills S, Stamos MJ: Sepsis In: Improved Outcomes in Colon and Rectal Surgery. Beck D, Hicks T, Margolin D, Whitlow C, Timmcke A (Eds) Informa Healthcare 2010
• Carmichael J, Stamos MJ: Single Site Laparoscopic Colectomy In: SAGES Fundamentals, 3rd Edition. Nguyen N, Scott-Conner S (Eds.) Springer-Verlag 2011
• Efron J, Stamos MJ: Laparoscopic Medial to Lateral Dissection for Left Colectomy In: Master Techniques in General Surgery, Colon and Rectal Surgery: Abdominal Operations, Ch. 9; pp 75-88. Fleshman J, Wexner S (Eds.) Lippincott, Williams and Wilkins Nov 2011
• Gandhi D, Stamos MJ: Polyps In: Colon and Rectal Surgery, an Illustrated Manual. Bailey HR, Billingham R, Snyder M, Stamos MJ (Eds.) Elsevier 2012

Audio visual:

• “En Bloc Laparoscopic-Assisted Extended Right Hemicolectomy for a T4 Lesion Involving the Abdominal Wall”. Video Presentation at the American Society of
  Colon and Rectal Surgeons annual meeting Boston, MA June 10-12, 2008
• “Natural Orifice Trans-Umbilical Cecectomy for Tubulovillous Adenoma at Appendiceal Orifice”. Video presentation at the Southwestern Surgical Congress Annual Meeting, San Diego, CA March 2009
• Bowel Preparation for Elective Colorectal Surgery: Helpful or Harmful? Audio Digest General Surgery 56 (12), 2009
• No Visible Scar Colectomy. ORLive Jan 28, 2010
• The Myth of the Bowel Prep. Audio Digest Gastroenterology 25 (11), 2011
• Colorectal Cancer Awareness webcast. CBS Healthwatch, March 2011
• SLIC Colectomy. Live Surgery SLIC (Strategic Laparoscopy for Improved Cosmesis) Summit, January 2012
• Colorectal Cancer Awareness webcast. CBS Healthwatch, March 2012