Frank Frizelle

frank frizelle Professional titles:
Professor of Surgery and Head of University Department of Surgery

Date of primary qualification: 1985

Current Institution:
University of Otago, Christchurch, New Zealand

Title of invited presentation:
Pelvic surgery for advanced and recurrent rectal cancer - where is the limit? Quality and outcome

Learning objectives:
To understand the issues involved in surgery for locally advanced and recurrent rectal cancer.

Summary of clinical/research background

My research expertise is in clinical based research and the translation of clinical problems into laboratory based research and vice versa, with special reference to colorectal disease especially inflammatory bowel disease, diverticular disease, colorectal cancer, AIN and physiological disturbances of bowel function following spinal cord injury. A more recent area of new development in my research has been regard to the medicolegal aspects of surgical healthcare provision and the impact of this on healthcare providers.

Relevant peer reviewed publications within last 5 years

Tapper R, Dixon L, Frampton C, Frizelle F. Impact of obesity on the cost of major colorectal surgery. Br J Surg. 2013 Jan;100(2):293-8. doi: 10.1002/bjs.8978. Epub 2012 Nov 22
Goonerante D, Gray C, Lim M, Dixon L, Dobbs B, Wakeman C, Frizelle F; Colorectal Lung Metastases Research Group (CRLMRG).Survival outcome in New Zealand after resection of colorectal cancer lung metastases. ANZ J Surg. 2012 Nov 27. doi: 10.1111/ans.12012
Bagshaw PF, Allardyce RA, Frampton CM, Frizelle FA, Hewett PJ, McMurrick PJ, Rieger NA, Smith JS, Solomon MJ, Stevenson AR; Australasian Laparoscopic Colon Cancer Study Group. Long-term outcomes of the australasian randomized clinical trial comparing laparoscopic and conventional open surgical treatments for colon cancer: the Australasian Laparoscopic Colon Cancer Study trial. Ann Surg. 2012 Dec;256(6):915-9. doi: 10.1097/SLA.0b013e3182765ff8
Pitama S, Cave T, Huria T, Lacey C, Cuddy J, Frizelle F. Exploring Maori health worker perspectives on colorectal cancer and screening. N Z Med J. 2012 Jun 8;125(1356):75-84
Lim G, Viney SK, Chapman BA, Frizelle FA, Gearry RB A prospective study of endoscopist-blinded colonoscopy withdrawal times and polyp detection rates in a tertiary hospital. N Z Med J. 2012 Jun 8;125(1356):52-9
Wilkes A, Griffin N, Dixon L, Dobbs B, Frizelle FA Mesenteric panniculitis: a paraneoplastic phenomenon? Dis Colon Rectum. 2012 Jul;55(7):806-9. doi: 10.1097/DCR.0b013e318252e286
Eglinton TW, Barclay ML, Gearry RB, Frizelle FA The spectrum of perianal Crohn's disease in a population-based cohort. Dis Colon Rectum. 2012 Jul;55(7):773-7. doi: 10.1097/DCR.0b013e31825228b0
Shaw D, Frizelle FAAvoidable complications following chest tube insertion.N Z Med J. 2012 May 11;125(1354):12-4.
Parnaby CN, Barrow EJ, Edirimanne SB, Parrott NR, Frizelle FA, Watson AJ Colorectal complications of end-stage renal failure and renal transplantation: a review.Colorectal Dis. 2012 Apr;14(4):403-15. Review
Frizelle FA. Proposed changes to the New Zealand Ethics Committees. N Z Med J. 2012 Jan 20;125(1348):10-1.
T Creagh. L Dixion. FA Frizelle Reconstruction with Vertical Rectus Abdominus Myocutaneous Flap in Advanced Pelvic Malignancy Journal of Plastic, Reconstructive & Aesthetic Surgery Ms. Ref. No.: JPRAS-D-11-00351R1
D. A. Westwood, T. W. Eglinton and F. A. Frizelle Authors’ reply: Routine colonoscopy following acute uncomplicated diverticulitis (Br J Surg 2011; 98: 1630–1634) Br J Surg 2012
99; 300-1.
Eglinton TW, Roberts R, Pearson J, Barclay M, Merriman TR, Frizelle FA, Gearry RB. Clinical and Genetic Risk Factors for Perianal Crohn's Disease in a Population-Based Cohort. Am J Gastroenterol. 2011 Dec 13. doi: 10.1038/ajg.2011.437
Macfarlane K, Dixon L, Wakeman CJ, Robertson GM, Eglinton TW, Frizelle FA. The process and outcomes of a nurse led colorectal cancer follow up clinic. Colorectal Dis. 2011 Dec 19. doi: 10.1111/j.1463-1318.2011.02923.x.
Parnaby CN, Barrow EJ, Edirimanne SB, Parrott NR, Frizelle FA, Watson AJM. Colorectal complications of end-stage renal failure and renal transplantation: a review. Colorectal Dis. 2010 Nov 4. doi: 10.1111/j.1463-1318.2010.02491.
Ooi K, Frizelle FA, Ong EJS, Faragher I. Current practice in preoperative therapy and surgical management of locally advanced rectal cancer: A bi-national survey. Colorectal Dis. 2011 Sep 7. doi: 10.1111/j.1463-1318.2011.02813.x.
Manar Khashram, Frank A Frizelle, Colonoscopy- A Rare Cause of Pancreatitis N Z Med J. 2011 Nov 4;124(1345):74-6
Anita Fitzgerald, Frank Frizelle, Mark Jeffery, Adrian Balasingam, Jan Casey, Judith Collett, Teresa Lynch, Denise Robbins, Adrian Secker, Tane Taylor, Clint Teague, Iain Ward, Jessica Berentson-Shaw Summary of guidance for the management of early bowel cancer NZ Med J. 2011; 124; 1337.124 No 1337
Westwood DA, Eglinton TW, Frizelle FA Routine colonoscopy following acute uncomplicated diverticulitis. Br J Surg. 2011 Nov 98(11):1630-4.
Parnaby C, Bailey W, Balasingam A, Beckert L, Eglinton T, Fife J, Frizelle F, Jeffery M, Watson A.Pulmonary staging in colorectal cancer: a review.Colorectal Dis. 2011 Mar 17. doi: 10.1111/j.1463-1318.2011.02601.x
Stabler A, Frizelle FA. Editorial Note on: The importance of verification and beta testing. Spinal Cord. 2011 May 10. [Epub ahead of print] No abstract available
Randall A Allardyce , Philip F Bagshaw, Christopher M Frampton , Francis A Frizelle, Peter J Hewett, Nicholas A Rieger, J. Shona Smith, Michael J Solomon, Andrew RL Stevenson, for the Australasian Laparoscopic Colon Cancer Study (ALCCaS) Group. The ethical disclosure of surgical trial short-term data. ANZJSurg 2011 Mar;81(3):125-31. doi: 10.1111/j.1445-2197.2010.05433.x. Epub 2010 Aug 16
Ganly P, Downing J, Stiven P, Frizelle F, Badami K. Clinical and serological diagnoses of a patient with vancomycin-induced thrombocytopenia. Transfus Med. 2011 Apr;21(2):137-9. doi: 10.1111/j.1365-3148.2010.01052.x. Epub 2010 Nov 18
Drazen JM, de Leeuw PW, Laine C, Mulrow C, DeAngelis CD, Frizelle FA, Godlee F, Haug C, Hébert PC, James A, Kotzin S, Marusic A, Reyes H, Rosenberg J, Sahni P, Van Der Weyden MB, Zhaori G.Toward more uniform conflict disclosures--the updated ICMJE reporting form for disclosure of potential conflicts of interest. Rev Med Chil. 2010 Jul;138(7):801-3.
Drazen JM, de Leeuw PW, Laine C, Mulrow C, DeAngelis CD, Frizelle FA, Godlee F, Haug C, Hébert PC, James A, Kotzin S, Marusic A, Reyes H, Rosenberg J, Sahni P, Van Der Weyden MB, Zhaori G.Toward more uniform conflict disclosures--the updated ICMJE reporting form for disclosure of potential conflicts of interest. Chin Med J (Engl). 2010 Jul;123(13):1621-2.
Drazen JM, de Leeuw PW, Laine C, Mulrow C, DeAngelis CD, Frizelle FA, Godlee F, Haug C, Hébert PC, James A, Kotzin S, Marusic A, Reyes H, Rosenberg J, Sahni P, Van Der Weyden MB, Zhaori G.Toward more uniform conflict disclosures--the updated ICMJE reporting form for disclosure of potential conflicts of interest. Med J Aust. 2010 Jul 5;193(1):7-8.
Drazen JM, De Leeuw PW, Laine C, Mulrow C, Deangelis CD, Frizelle FA, Godlee F, Haug C, Hébert PC, James A, Kotzin S, Marusic A, Reyes H, Rosenberg J, Sahni P, Van Der Weyden MB, Zhaori G.Toward more uniform conflict disclosures: the updated ICMJE conflict of interest reporting form. Natl Med J India. 2010 Jul-Aug;23(4):196-7.
Frank A Frizelle. The New Zealand Medical Journal, Thomson Reuters ISI, and the impact factor. NZMJ 2010 Vol 123 No 1323 6-8 URL http://www.nzma.org.nz/journal/123-1323/4363/content.pdf
Frank A Frizelle The missing manuscript NZMJ 30 July 2010, Vol 123 No 1319; ISSN 1175 8716 URL: http://www.nzma.org.nz/journal/123-1319/4252/
Sabanli M, Balasingam A, Bailey W, Eglinton T, Hider P, Frizelle FA Computed tomographic colonography in the diagnosis of colorectal cancer. Br J Surg. 2010 Aug;97(8):1291-4.
Eglinton T, Nguyen T, Raniga S, Dixon L, Dobbs B, Frizelle FA.Patterns of recurrence in patients with acute diverticulitis. Br J Surg. 2010 Jun;97(6):952-7
Kennedy RR, Lee A, Frizelle FA. Influence of general health and degree of surgical insult on long-term survival. Br J Surg. 2010 May;97(5):782-8
Allardyce RA, Bagshaw PF, Frampton CM, Frizelle FA, Hewett PJ, Rieger NA, Smith JS, Solomon MJ, Stevenson AR; Australasian Laparoscopic Colon Cancer Study Group. Australasian Laparoscopic Colon Cancer Study shows that elderly patients may benefit from lower postoperative complication rates following laparoscopic versus open resection. Br J Surg. 2010 Jan;97(1):86-91
Drazen JM, de Leeuw PW, Laine C, Mulrow C, Deangelis CD, Frizelle FA, Godlee F, Haug C, Hébert PC, James A, Kotzin S, Marusic A, Reyes H, Rosenberg J, Sahni P, Van Der Weyden MB, Zhaori G. Toward more uniform conflict disclosures: updated ICMJE conflict of interest reporting form. CMAJ. 2010 Jul 13;182(10):E425. Epub 2010 Jul 2.
Drazen JM, de Leeuw PW, Laine C, Mulrow C, Deangelis CD, Frizelle FA, Godlee F, Haug C, Hébert PC, James A, Kotzin S, Marusic A, Reyes H, Rosenberg J, Sahni P, Van Der Weyden MB, Zhaori G. Toward more uniform conflict disclosures--the updated ICMJE conflict of interest reporting form. Tidsskr Nor Laegeforen. 2010 Jul 1;130(13):E1-2.
Drazen JM, de Leeuw PW, Laine C, Mulrow C, DeAngelis CD, Frizelle FA, Godlee F, Haug C, Hébert PC, James A, Kotzin S, Marusic A, Reyes H, Rosenberg J, Sahni P, Van der Weyden MB, Zhaori G. Toward more uniform conflict disclosures: the updated ICMJE conflict of interest reporting form. JAMA. 2010 Jul 14;304(2):212-3. Epub 2010 Jul 1.
Drazen JM, de Leeuw PW, Laine C, Mulrow C, Deangelis CD, Frizelle FA, Godlee F, Haug C, Hébert PC, James A, Kotzin S, Marusic A, Reyes H, Rosenberg J, Sahni P, Van Der Weyden MB, Zhaori Toward More Uniform Conflict Disclosures: The Updated ICMJE Conflict of Interest Reporting Form. Ann Intern Med. 2010 Jul 1. [Epub ahead of print]
Drazen JM, de Leeuw PW, Laine C, Mulrow C, Deangelis CD, Frizelle FA, Godlee F, Haug C, Hébert PC, Horton R, Kotzin S, Marusic A, Reyes H, Rosenberg J, Sahni P, Van Der Weyden MB, Zhaori G. Towards more uniform conflict disclosures: the updated ICMJE conflict of interest reporting form. BMJ. 2010 Jun 30;340:c3239. doi: 10.1136/bmj.c3239.
Drazen JM, de Leeuw PW, Laine C, Mulrow C, DeAngelis CD, Frizelle FA, Godlee F, Haug C, Hébert PC, James A, Kotzin S, Marusic A, Reyes H, Rosenberg J, Sahni P, Van Der Weyden MB, Zhaori G. Toward more uniform conflict disclosures: the updated ICMJE conflict of interest reporting form. Dan Med Bull. 2010 Jul;57(7):A4168.
Drazen JM, de Leeuw PW, Laine C, Mulrow C, DeAngelis CD, Frizelle FA, Godlee F, Haug C, Hébert PC, James A, Kotzin S, Marusic A, Reyes H, Rosenberg J, Sahni P, Van Der Weyden MB, Zhaori G Toward more uniform conflict disclosures: the updated ICMJE conflict of interest reporting form. N Z Med J. 2010 Jul 16;123(1318):12-4.
Eglinton T, Reilly M, Chang C, Barclay M, Frizelle F, Gearry R Ileal disease is associated with surgery for perianal disease in a population-based Crohn's disease cohort. Br J Surg. 2010 Jul;97(7):1103-9
Drazen JM, de Leeuw PW, Laine C, Mulrow C, DeAngelis CD, Frizelle FA, Godlee F, Haug C, Hébert PC, James A, Kotzin S, Marusic A, Reyes H, Rosenberg J, Sahni P, Van der Weyden MB, Zhaori G.Toward more uniform conflict disclosures--the updated ICMJE conflict of interest reporting form. N Engl J Med. 2010 Jul 8;363(2):188-9. Epub 2010 Jul 1.
Keenan JI, Beaugie CR, Jasmann B, Potter HC, Collett JA, Frizelle FA.. Helicobacter species in the human colon.Colorectal Dis. 2010 Jan;12(1):48-53
Drazen JM, Van Der Weyden MB, Sahni P, Rosenberg J, Marusic A, Laine C, Kotzin S, Horton R, Hébert PC, Haug C, Godlee F, Frizelle FA, de Leeuw PW, Deangelis CD.
Uniform Format for Disclosure of Competing Interests in ICMJE Journals. J Am Dent Assoc. 2010 Feb;141(2):131-2
Drazen JM, Van Der Weyden MB, Sahni P, Rosenberg J, Marusic A, Laine C, Kotzin S, Horton R, Hébert PC, Haug C, Godlee F, Frizelle FA, de Leeuw PW, Deangelis CD. Uniform Format for Disclosure of Competing Interests in ICMJE Journals. Ann Intern Med. 2010 Jan 19;152(2):125-6
Fife J, Raniga S, Hider PN, Frizelle FA. Folic Acid Supplementation and Colorectal Cancer Risk; A Meta-analysis. Colorectal Dis. 2009 Oct 27. [Epub ahead of print]
Drazen JM, Van Der Weyden MB, Sahni P, Rosenberg J, Marusic A, Laine C, Kotzin S, Horton R, Hébert PC, Haug C, Godlee F, Frizelle FA, de Leeuw PW, Deangelis CD. Uniform Format for Disclosure of Competing Interests in ICMJE Journals. Med J Aust. 2009 Nov 2;191(9):475-6
Drazen JM, Van Der Weyden MB, Sahni P, Rosenberg J, Marusic A, Laine C, Kotzin S, Horton R, Hébert PC, Haug C, Godlee F, Frizelle FA, de Leeuw PW, Deangelis CD. Uniform Format for Disclosure of Competing Interests in ICMJE Journals. N Z Med J. 2009 Oct 30;122(1305):12-4.
Frank Frizelle. For public health doctors, alcohol is the new tobacco NZMJ 2009, 122;1303, 9. http://www.nzma.org.nz/journal/122-1303/3803/content.pdf
Drazen JM, Van Der Weyden MB, Sahni P, Rosenberg J, Marusić A, Laine C, Kotzin S, Horton R, Hébert PC, Haug C, Godlee F, Frizelle FA, de Leeuw PW, DeAngelis CD. Uniform format for disclosure of competing interests in ICMJE Journals.Croat Med J. 2009 Oct;50(5):427-8.
Drazen JM, Van Der Weyden MB, Sahni P, Rosenberg J, Marusic A, Laine C, Kotzin S, Horton R, Hébert PC, Haug C, Godlee F, Frizelle FA, de Leeuw PW, Deangelis CD. Uniform format for disclosure of competing interests in ICMJE journals. Lancet. 2009 Oct 14. [Epub ahead of print].
Frizelle F. Is this reference correct? N Z Med J. 2009 Aug 21;122(1301):8-9. http://www.nzma.org.nz/journal/122-1301/3756/content.pdf
Drazen JM, Van Der Weyden MB, Sahni P, Rosenberg J, Marusic A, Laine C, Kotzin S, Horton R, Hébert PC, Haug C, Godlee F, Frizelle FA, de Leeuw PW, Deangelis CD. Uniform Format for Disclosure of Competing Interests in ICMJE Journals. Ann Intern Med. 2009 Oct 13. [Epub ahead of print]
Drazen JM, Van Der Weyden MB, Sahni P, Rosenberg J, Marusic A, Laine C, Kotzin S, Horton R, Hébert PC, Haug C, Godlee F, Frizelle FA, de Leeuw PW, Deangelis CD. Uniform Format for Disclosure of Competing Interests in ICMJE Journals. JAMA. 2009 Oct 13. [Epub ahead of print]
Drazen JM, Van Der Weyden MB, Sahni P, Rosenberg J, Marusic A, Laine C, Kotzin S, Horton R, Hébert PC, Haug C, Godlee F, Frizelle FA, de Leeuw PW, Deangelis CD. Uniform Format for Disclosure of Competing Interests in ICMJE Journals.N Engl J Med. 2009 Oct 13. [Epub ahead of print]
Drazen JM, Van Der Weyden MB, Sahni P, Rosenberg J, Marusic A, Laine C, Kotzin S, Horton R, Hébert PC, Haug C, Godlee F, Frizelle FA, de Leeuw PW, Deangelis CD. Uniform format for disclosure of competing interests in ICMJE journals.CMAJ. 2009 Oct 13. [Epub ahead of print]
Drazen JM, Van Der Weyden MB, Sahni P, Rosenberg J, Marusic A, Laine C, Kotzin S, Horton R, Hébert PC, Haug C, Godlee F, Frizelle FA, de Leeuw PW, DeAngelis CD. Disclosure of competing interests. BMJ. 2009 Oct 12;339
Andrew Ing, Richard B Gearry, Martin Whitehead, Ian G Faragher Bruce Dobbs, Frank A Frizelle. Immunomodulation Does Not Alter Histology in Resected Crohn’s Disease. In press Tech Coloproctol. 2009 Sep 23. [Epub ahead of print]
Frank Frizelle. Consent for case reports and medical images NZMJ 2009 http://www.nzma.org.nz/journal/122-1300/3743/content.pdf
Simon Janes, Alan Meagher, Ian G Faragher Susan Shedda Frank A Frizelle The place of elective surgery following acute diverticulitis in young patients; When is Surgery indicated? An analysis of the literature. Dis Colon Rectum. 2009 May;52(5):1008-16
J Armatige FA Frizelle Apples or oranges: Reversing Hartmann’s. Dis Colon Rectum. 2009 May;52(5):1027; author reply 1028.
Richard Tapper and Frank Frizelle. An Abdominal Pearl NZMJ 2009 N Z Med J. 2009 Aug 7;122(1300):76-7. http://www.nzma.org.nz/journal/122-1300/3729/content.pdf
Frizelle F Cancer in New Zealand.N Z Med J. 2009 May 8;122(1294):7-9.
Edwardes B, Frizelle F Globalisation and its impact on the South Pacific. N Z Med J. 2009 Mar 13;122(1291):10-3
Selena C. Young , Michael J. Solomon, George Hruby, Frank A. Frizelle. Review of 120 anal cancer patients Colorectal Dis. 2008 Oct 25. [Epub ahead of print]
Peter J Hewett, Randall Allardyce, Philip Bagshaw, Frank A. Frizelle, Nicholas A Rieger, Michael J Solomon, Andrew RL Stevenson, for the Australasian Laparoscopic Colon Cancer Study (ALCCaS) Group Short-term Outcomes of the Australasian, Randomised, Clinical Study comparing Laparoscopic and Conventional Open Surgical Treatments of Colon Cancer: The ALCCaS Trial. Annuals of Surgery 2008 248;728-38
Randall A Allardyce , Philip F Bagshaw , Christopher M Frampton , Francis A Frizelle, Peter J Hewett, Nicholas A Rieger , J. Shona Smith , Michael J Solomon , Andrew RL Stevenson , for the Australasian Laparoscopic Colon Cancer Study (ALCCAS) Group . Australasian Study Comparing Laparoscopic And Open Surgery For Colon Cancer (ALCCAS) ANZJS 2008, 78;840-7.
Randall A Allardyce, Philip F Bagshaw, Christopher M Frampton, Francis A Frizelle, Peter J Hewett , Nicholas A Rieger, Shona Smith, Michael J Solomon, Andrew RL Stevenson for the Australasian Laparoscopic Colon Cancer Study (ALCCaS) Group. Perspective; The Australasian Laparaoscopic Colon Cancer Study (ALCCaS) ANZJS 2008; 78, 832-3
Frizelle FA.What are the major political parties' healthcare policies for New Zealand? N Z Med J. 2008 Oct 3;121(1283):12-4.
Ing A, Lienert A, Frizelle F.Medical image. CT colonography for colovesical fistula. N Z Med J. 2008 Aug 8;121(1279):105-8.
Frizelle FA. Defamatory articles or not? N Z Med J. 2008 Aug 8;121(1279):16-7
Phitayakorn R, Delaney CP, Reynolds HL, Champagne BJ, Heriot AG, Neary P, Senagore AJ; International Anastomotic Leak Study Group.Standardized algorithms for management of anastomotic leaks and related abdominal and pelvic abscesses after colorectal surgery. World J Surg. 2008 Jun;32(6):1147-56.
Sutherland AD, Gearry RB, Frizelle FA. Review of Fecal Biomarkers in Inflammatory Bowel Disease.Dis Colon Rectum. 2008 Jun 10. [Epub ahead of print]
Frizelle FA. Resourcing for the growing burden of elderly patients with cancer. ANZ J Surg. 2008 Jun;78(6):428-9..
Frizelle F.The Author Replies.Dis Colon Rectum. 2008 Jun 3. [Epub ahead of print]
Sutherland AD, Faragher IG, Frizelle FA.Intradermal injection of methylene blue for the treatment of refractory pruritus ani. Colorectal Dis. 2008 May 29. [Epub ahead of print]
Paddison JS, Booth RJ, Cameron LD, Robinson E, Frizelle FA, Hill AG.Fatigue after Colorectal Surgery and Its Relationship to Patient Expectations. J Surg Res. 2008 Feb 29. [Epub ahead of print]
Peter J. Lee, Sumit Raniga, Deepak K Biyani, Angus J M Watson, Ian G Faragher, Frank A. Frizelle Sacrococcygeal Pilonidal Disease. Colorectal Dis. 2008 Mar 29; [Epub ahead of print]
John S Munday, Frank Frizelle, Martin Whitehead. Normal mismatch repair protein expression in ovine intestinal adenocarcinomas. Vet Pathol. 2008 Jan;45(1):3-6.
C.J. Wakeman, B.R. Dobbs, F.A. Frizelle, I. P. Bissett, E.R. Dennett A. Hill M.W. Thompson-Fawcett. The impact of splenectomy on outcome after resection for colorectal cancer; A multicentre nested paired cohort study. Dis Colon Rectum 2008 Feb;51(2):213-7. Epub 2008 Jan 4
Alexander G Heriot, Christopher M Byrne, Peter Lee, Bruce Dobbs, Henry Tilney, Michael J Solomon, John Mackay, Frank Frizelle Extended radical resection - the choice for locally recurrent rectal cancer Dis Colon Rectum 2008 Mar;51(3):284-291. Epub 2008 Jan 19Jan 19;