Glen DohertyYear of primary qualification: 1998

Current institutions: St Vincent's University Hospital, University College Dublin, Ireland

Title of presentation: Update on pathogenesis and medical treatment (Symposium: Ulcerative colitis)

Learning objectives: Understand the latest developments in understanding of the causes of ulcerative colitis and factors associated with progression; Appreciate the importance of a personalized approach to optimizing medical management in ulcerative colitis; Gain insight into the potential role of newly approved biologic therapies focusing on safety and efficacy

Clinical/research background

Glen Doherty graduated from Trinity College Dublin. He completed his PhD degree in 2006 in the area of colorectal cancer at RCSI and the Conway Institute at University College Dublin, focusing on eicosanoid signalling pathways. He spent a period of further specialist training in the USA at Beth Israel Deaconess Medical Centre and Harvard Medical School, Boston where he undertook a post-doctoral research programme with Professor Simon Robson in purinergic signaling in mucosal immunology and IBD.

Since 2010 he has worked as a Consultant Gastroenterologist at the Centre for Colorectal Disease at St Vincent's University Hospital and University College Dublin.

Glen has numerous peer-reviewed publications in the areas of inflammatory bowel disease, colorectal cancer and endoscopy. He is Honorary Treasurer of the Irish Society of Gastroenterology and National Representative for the European Crohn's and Colitis Organisation.

Relevant peer-reviewed publications

  1. Gibson DJ, Murphy DJ, Smyth AE, McEvoy SH, Keegan D, Byrne K, Mulcahy HE, Cullen G, Malone DE, Doherty GA. Magnetic resonance enterography findings as predictors of clinical outcome following antitumor necrosis factor treatment in small bowel Crohn's disease. Eur J Gastroenterol Hepatol. 2015 Aug;27(8):956-62. PMID: 26049706.
  2. Flood B, Oficjalska K, Laukens D, Fay J, O'Grady A, Caiazza F, Heetun Z, Mills KH, Sheahan K, Ryan EJ, Doherty GA, Kay E, Creagh EM. Altered expression of caspases-4 and -5 during inflammatory bowel disease and colorectal cancer: Diagnostic and therapeutic potential. Clin Exp Immunol. 2015 Jul;181(1):39-50. PMID: 25943872
  3. Lee CS, Murphy DJ, McMahon C, Nolan B, Cullen G, Mulcahy H, Sheahan K, Barnes E, Fennelly D, Ryan EJ, Doherty GA. Visceral Adiposity is a Risk Factor for Poor  Prognosis in Colorectal Cancer Patients Receiving Adjuvant Chemotherapy. J Gastrointest Cancer. 2015 Apr 2. PubMed PMID: 25832480. Gibson DJ, Heetun ZS, Redmond CE, Nanda KS, Kee

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